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Regulation of cell survival by resveratrol involves inhibition of NFκB-regulated gene expression in prostate cancer cells
(2009)
BACKGROUND. Polyphenols have been proposed as antitumoral agents. We have shown that resveratrol (RES) induced cell cycle arrest and promoted apoptosis in prostate cancer cells by inhibition of the PI3K pathway. The RES ...
Soluble factors produced by PC-3 prostate cells decrease collagen content and mineralisation rate in fetal rat osteoblasts in culture
(Stockton Press, 1996)
Approximately 70% of patients with prostate cancer develop bone metastases in the advanced state
of the disease. In the present study, we sought to test the hypothesis that prostatic cancer cells produce factors
that ...
Alpha7 Nicotinic Acetylcholine Receptor Expression and Activity During Neuronal Differentiation of PC12 Pheochromocytoma Cells
(HUMANA PRESS INC, 2010)
Nicotinic acetylcholine receptors (nAChR) exert pivotal roles in synaptic transmission, neuroprotection and differentiation. Particularly, homomeric alpha 7 receptors participate in neurite outgrowth, presynaptic control ...
Exposure to bacteriophages t4 and m13 increases integrin gene expression and impairs migration of human pc-3 prostate cancer cells
(2021-10-01)
The interaction between bacteriophages and integrins has been reported in different cancer cell lines, and efforts have been undertaken to understand these interactions in tumor cells along with their possible role in gene ...
Envolvimento da proteína neuronal sensora de cálcio-1 (NCS-1) na sinalização muscarínica em células PC12
(Universidade Federal de Minas GeraisUFMG, 2007-06-19)
Neuronal calcium sensor-1 (NCS-1) belongs to the superfamily of EF-hand Ca2+ binding protein. Overexpression of NCS-1 was implicated on potentiation of synaptic transmission and plasticity in many experimental models. In ...
Stimulating effect of palmitate and insulin on cell migration and proliferation in PNT1A and PC3 prostate cells: Counteracting role of metformin
(2018-07-01)
Background: A potential association between obesity and prostate cancer has been proposed. Metformin, an antidiabetes drug, has antiproliferative effects being proposed for cancer treatment. However, under intense proliferative ...
Decreased c-Abl activity in PC-3 and LNCaP prostate cancer cells overexpressing the early growth response-1 protein
(Spandidos Publ, 2014)
Early growth response-1 (Egr-1) and the non-receptor protein tyrosine kinase (c-Abl) are 2 response genes that can act as regulators of cell growth and apoptosis in response to stress. Both Egr-1 and c-Abl regulate cell ...
Improved photodynamic action of nanoparticles loaded with indium (III) phthalocyanine on MCF-7 breast cancer cells
(Springer, 2013-09-01)
Indium (III) phthalocyanine (InPc) was encapsulated into nanoparticles of PEGylated poly (D,L-lactide-co-glycolide) (PLGA-PEG) to improve the photobiological activity of the photosensitizer. the efficacy of nanoparticles ...
Transcriptome of Two Canine Prostate Cancer Cells Treated With Toceranib Phosphate Reveals Distinct Antitumor Profiles Associated With the PDGFR Pathway
(2020-11-26)
Canine prostate cancer (PC) presents a poor antitumor response, usually late diagnosis and prognosis. Toceranib phosphate (TP) is a nonspecific inhibitor of receptor tyrosine kinases (RTKs), including vascular endothelial ...